Trial intelligence / Profile preview

KEYNOTE-412: Pembrolizumab with concurrent chemoradiotherapy and maintenance vs chemoradiotherapy alone in locally advanced head and neck squamous cell carcinoma

jRCT2080223584Phase 3Completed

Sponsor
Merck & Co.
Start
Jul 2017
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
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Overview

Phase 3, randomised, double-blind trial of pembrolizumab in head and neck squamous cell carcinoma (HNSCC), oropharyngeal squamous cell carcinoma (OPSCC), laryngeal squamous cell carcinoma (LSCC) and 2 more (2 arms), sponsored by Merck & Co. Started Jul 2017; status: completed.

02

Drugs

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Conditions

head and neck squamous cell carcinoma (HNSCC)oropharyngeal squamous cell carcinoma (OPSCC)laryngeal squamous cell carcinoma (LSCC)squamous cell carcinoma of the hypopharynxOral Mucosal Carcinoma

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