Trial intelligence / Profile preview

Durvalumab and Tremelimumab vs Sorafenib in Advanced Hepatocellular Carcinoma

jRCT2080223793Phase 3Completed

Sponsor
AstraZeneca
Start
Feb 2018
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, open-label trial in hepatocellular carcinoma (HCC) comparing Durvalumab + Tremelimumab with Sorafenib (2 arms). Started Feb 2018; status: completed.

02

Drugs

durvalumabtremelimumabsorafenib
03

Conditions

hepatocellular carcinoma (HCC)

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