Trial intelligence / Profile preview

KEYNOTE-789: Pembrolizumab + platinum/pemetrexed in TKI-resistant EGFR-mutated metastatic non-squamous NSCLC

jRCT2080223961Phase 3Completed

Sponsor
Merck & Co.
Start
Jul 2018
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
01

Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing Pembrolizumab + pemetrexed + platinum with Placebo + pemetrexed + platinum (2 arms). Primary endpoints: Overall survival and Progression-free survival (BICR). Started Jul 2018; status: completed.

02

Drugs

03

Conditions

non-small cell lung cancer (NSCLC)

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