Trial intelligence / Profile preview

KEYNOTE-495 (KeyImPaCT) biomarker-directed pembrolizumab-based combinations in advanced NSCLC

jRCT2080224552Phase 2Completed

Sponsor
Merck & Co.
Start
Feb 2019
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
01

Overview

Phase 2, open-label trial of pembrolizumab, lenvatinib, favezelimab and quavonlimab in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Merck & Co. Primary endpoint: Objective response rate (ORR). Started Feb 2019; status: completed.

02

Drugs

pembrolizumablenvatinibfavezelimabquavonlimab
03

Conditions

non-small cell lung cancer (NSCLC)

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