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PACIFIC-4/RTOG-3515 durvalumab with SBRT in unresected stage I/II node-negative NSCLC

jRCT2080224593Phase 3Completed

Sponsor
AstraZeneca
Start
Mar 2019
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing SoC SBRT + durvalumab, SoC SBRT + placebo and SoC SBRT + osimertinib (3 arms). Started Mar 2019; status: completed.

02

Drugs

durvalumabosimertinib
03

Conditions

non-small cell lung cancer (NSCLC)

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