Trial intelligence / Profile preview

LEAP-007: Pembrolizumab with or without lenvatinib in treatment-naive metastatic NSCLC (PD-L1 TPS ≥1%)

jRCT2080224599Phase 3Completed

Sponsor
Merck & Co.
Start
Mar 2019
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
01

Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing Pembrolizumab + lenvatinib with Pembrolizumab + placebo (2 arms). Primary endpoint: Overall survival. Started Mar 2019; status: completed.

02

Drugs

pembrolizumablenvatinib
03

Conditions

non-small cell lung cancer (NSCLC)

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