Trial intelligence / Profile preview

Phase 1b study of retifanlimab (INCMGA00012), INCB001158, and their combination in Japanese participants with advanced solid tumors

jRCT2080224802Phase 1Completed

Sponsor
Incyte
Start
Jul 2019
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of retifanlimab and numidargistat in Nonhematologic neoplasms and solid tumor (3 arms), sponsored by Incyte. Primary endpoints: Recommended phase 2 dose (RP2D) of retifanlimab monotherapy, Recommended phase 2 dose (RP2D) of INCB001158 monotherapy and combination and 2 more. Started Jul 2019; status: completed.

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Drugs

retifanlimabnumidargistat
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Conditions

Nonhematologic neoplasmssolid tumor

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