Trial intelligence / Profile preview

LEAP-008: Pembrolizumab + lenvatinib vs docetaxel in previously treated metastatic NSCLC

jRCT2080224918Phase 3Completed

Sponsor
Merck & Co.
Start
Oct 2019
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Pembrolizumab + lenvatinib, Docetaxel and Lenvatinib monotherapy (3 arms). Primary endpoints: Overall survival (OS) and Progression-free survival (PFS). Started Oct 2019; status: completed.

02

Drugs

pembrolizumablenvatinibdocetaxel
03

Conditions

non-small cell lung cancer (NSCLC)

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