Trial intelligence / Profile preview

KEYNOTE-641: pembrolizumab plus enzalutamide versus placebo plus enzalutamide in metastatic castration-resistant prostate cancer

jRCT2080224920Phase 3Completed

Sponsor
Merck & Co.
Start
Oct 2019
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
01

Overview

Phase 3, randomised, double-blind trial in prostate cancer (PCa) comparing Pembrolizumab + enzalutamide with Placebo + enzalutamide (2 arms). Primary endpoints: Overall survival and Radiographic progression-free survival. Started Oct 2019; status: completed.

02

Drugs

pembrolizumabenzalutamide
03

Conditions

prostate cancer (PCa)

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