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Capmatinib plus pembrolizumab versus pembrolizumab alone in first-line advanced NSCLC with high PD-L1 expression

jRCT2080225053Phase 2Completed

Sponsor
Novartis
Start
Feb 2020
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
01

Overview

Phase 2, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Capmatinib + pembrolizumab with Pembrolizumab alone (2 arms). Primary endpoint: Progression-free survival. Started Feb 2020; status: completed.

02

Drugs

capmatinibpembrolizumab
03

Conditions

non-small cell lung cancer (NSCLC)

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