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Phase I/Ib study of subcutaneous NIZ985 (hetIL-15) with spartalizumab or tislelizumab in CPI-relapsed advanced solid tumors and lymphoma

jRCT2080225081Phase 1Completed

Sponsor
Novartis
Start
Feb 2020
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes
01

Overview

Phase 1, open-label trial of NIZ985 in Non-hematologic malignancy and lymphoma (3 arms), sponsored by Novartis. Primary endpoints: Safety and tolerability of NIZ985 alone and in combination with spartalizumab or tislelizumab and Recommended dose for expansion (RDE) of NIZ985. Started Feb 2020; status: completed.

02

Drugs

NIZ985
03

Conditions

Non-hematologic malignancylymphoma

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