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STIMULUS-MDS2: MBG453 plus azacitidine vs placebo plus azacitidine in higher-risk MDS or CMML-2

jRCT2080225135Phase 3Completed

Sponsor
Novartis
Start
Mar 2020
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, double-blind trial in myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) comparing MBG453 plus azacitidine with Placebo plus azacitidine (2 arms). Primary endpoint: Overall survival. Started Mar 2020; status: completed.

02

Drugs

sabatolimab
03

Conditions

myelodysplastic syndrome (MDS)chronic myelomonocytic leukemia (CMML)

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