Trial intelligence / Profile preview

LEAP-010: Pembrolizumab with or without lenvatinib in first-line PD-L1–selected recurrent or metastatic head and neck squamous cell carcinoma

jRCT2080225144Phase 3Completed

Sponsor
Merck & Co.
Start
Mar 2020
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
01

Overview

Phase 3, randomised, double-blind trial in head and neck squamous cell carcinoma (HNSCC) comparing Pembrolizumab + lenvatinib with Pembrolizumab + placebo (2 arms). Started Mar 2020; status: completed.

02

Drugs

pembrolizumablenvatinib
03

Conditions

head and neck squamous cell carcinoma (HNSCC)

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