Trial intelligence / Profile preview

Randomized Double-blind Placebo-controlled Study of Pelacarsen (TQJ230) on Cardiovascular Outcomes in Patients With Established Cardiovascular Disease and Elevated Lipoprotein(a)

jRCT2080225280Phase 3Completed

Sponsor
Novartis
Start
Jul 2020
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

Phase 3, randomised, double-blind trial in cardiac morbidity, myocardial infarction (MI), ischemic stroke and 2 more comparing Pelacarsen 80 mg monthly with Placebo (2 arms). Started Jul 2020; status: completed.

02

Drugs

pelacarsen
03

Conditions

cardiac morbiditymyocardial infarction (MI)ischemic strokearteriosclerosis obliteranslipoprotein(a) hyperlipoproteinemia (Lp(a))

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