Trial intelligence / Profile preview

Phase III Crovalimab vs Eculizumab in PNH Patients on Complement Inhibitors

jRCT2080225334Phase 3Completed

Sponsor
Chugai Pharmaceutical Co., Ltd.
Start
Aug 2020
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, open-label trial of crovalimab in paroxysmal nocturnal hemoglobinuria (PNH) (2 arms), sponsored by Chugai Pharmaceutical Co., Ltd. Primary endpoints: Safety of crovalimab vs eculizumab, Pharmacokinetics of crovalimab and 2 more. Started Aug 2020; status: completed.

02

Drugs

crovalimab
03

Conditions

paroxysmal nocturnal hemoglobinuria (PNH)

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