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Phase 2 randomized open-label study of JNJ-73763989 ± JNJ-56136379 with nucleos(t)ide analog and pegylated interferon alfa-2a in treatment-naive HBeAg-positive chronic hepatitis B

jRCT2080225335Phase 2Completed

Sponsor
Janssen Pharmaceutical
Start
Aug 2020
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

Phase 2, randomised, open-label trial of tomligisiran in Chronic Hepatitis B (CHB), sponsored by Janssen Pharmaceutical. Started Aug 2020; status: completed.

02

Drugs

tomligisiran
03

Conditions

Chronic Hepatitis B (CHB)

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