Trial intelligence / Profile preview

Amivantamab + lazertinib versus osimertinib versus lazertinib in first-line EGFR-mutated advanced or metastatic non-small cell lung cancer

jRCT2080225336Phase 3Completed

Sponsor
Janssen Pharmaceutical
Start
Aug 2020
Modality
Small Molecules, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing Amivantamab + lazertinib, Osimertinib + matching placebo and Lazertinib + matching placebo (3 arms). Started Aug 2020; status: completed.

02

Drugs

amivantamablazertinibosimertinib
03

Conditions

non-small cell lung cancer (NSCLC)

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