Trial intelligence / Profile preview

Dabrafenib + trametinib in pediatric refractory BRAF V600-mutant solid tumors

jRCTs011220017Completed

Sponsor
crowdfunding
Start
May 2023
Modality
Small Molecules
Countries
1
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Overview

Open-label, single-arm trial of dabrafenib + trametinib and trametinib in Nonhematologic neoplasms, brain neoplasm and histiocytosis, sponsored by crowdfunding. Primary endpoint: Confirmed objective response rate by RECIST v1.1 up to Week 24. Started May 2023; status: completed.

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Drugs

dabrafenib + trametinibtrametinib
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Conditions

Nonhematologic neoplasmsbrain neoplasmhistiocytosis

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