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Dose-dependent effect of pyrimethamine on MATE1/2K biomarkers and metformin PK
jRCTs031180125Completed
- Sponsor
- Pfizer
- Start
- Apr 2019
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Randomised, open-label trial of pyrimethamine (2 arms), sponsored by Pfizer. Primary endpoints: Kinetic parameters of endogenous substrates with and without metformin and pyrimethamine and Pharmacokinetics of metformin and pyrimethamine. Started Apr 2019; status: completed.
02
Drugs
pyrimethamine
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