Trial intelligence / Profile preview

ACHILLES study of afatinib versus platinum-pemetrexed chemotherapy in EGFR uncommon mutation-positive advanced non-small cell lung cancer

jRCTs031180175Phase 3Completed

Sponsor
Japan Thoracic Oncology Research Group
Start
Apr 2019
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of afatinib, cisplatin, carboplatin and pemetrexed in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Japan Thoracic Oncology Research Group. Primary endpoint: Progression-free survival. Started Apr 2019; status: completed.

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Drugs

afatinibcisplatincarboplatinpemetrexed
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Conditions

non-small cell lung cancer (NSCLC)

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