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COMET trial of luseogliflozin versus glimepiride with ranibizumab for diabetic macular edema in type 2 diabetes

jRCTs031180210Completed

Sponsor
Taisho Pharmaceutical
Start
Mar 2019
Modality
Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Randomised, open-label trial in diabetic macular edema (DME) and type 2 diabetes mellitus (T2DM) comparing Ranibizumab + luseogliflozin with Ranibizumab + glimepiride (2 arms). Primary endpoint: Intergroup difference in number of anti-VEGF intravitreal injections. Started Mar 2019; status: completed.

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Drugs

ranibizumabluseogliflozinglimepiride
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Conditions

diabetic macular edema (DME)type 2 diabetes mellitus (T2DM)

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