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OPAL regimen phase 2 study in EGFR-mutated advanced non-small cell lung cancer

jRCTs031180226Phase 2Completed

Sponsor
North East Japan Study Group
Start
Jul 2019
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of osimertinib, cisplatin, carboplatin and pemetrexed in non-small cell lung cancer (NSCLC), sponsored by North East Japan Study Group. Primary endpoints: Safety and Objective response rate. Started Jul 2019; status: completed.

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Drugs

osimertinibcisplatincarboplatinpemetrexed
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Conditions

non-small cell lung cancer (NSCLC)

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