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Efficacy of adding metformin to aspirin for rectal aberrant crypt foci
jRCTs031180253Active, not recruiting
- Sponsor
- Ministry of Education, Culture, Sports, Science and Technology
- Start
- Sep 2017
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Randomised, double-blind trial in colon adenoma, Colorectal carcinoma in situ and aberrant crypt foci (ACF) comparing Aspirin + placebo with Aspirin + metformin (2 arms). Primary endpoint: Change in number of rectal aberrant crypt foci after 8 weeks. Started Sep 2017; status: active, not recruiting.
02
Drugs
metforminaspirin
03
Conditions
colon adenomaColorectal carcinoma in situaberrant crypt foci (ACF)
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