Trial intelligence / Profile preview

SCRT plus CAPOX versus SCRT plus CAPOXIRI for locally advanced rectal cancer

jRCTs031220342Phase 3Recruiting

Sponsor
Japan Agency for Medical Research and Development
Start
Nov 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Phase 3, randomised, open-label trial of capecitabine, oxaliplatin and irinotecan in rectal cancer (2 arms), sponsored by Japan Agency for Medical Research and Development. Primary endpoint: Organ preservation adapted disease free survival. Started Nov 2022; status: recruiting.

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Drugs

capecitabineoxaliplatinirinotecan
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Conditions

rectal cancer

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