Trial intelligence / Profile preview

REGISTA-K

jRCTs031220568Active, not recruiting

Sponsor
AstraZeneca
Start
Oct 2023
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Randomised, double-blind trial in hyperkalemia and heart failure with reduced ejection fraction (HFrEF) comparing Lokelma arm with Placebo arm (2 arms). Primary endpoint: Achievement of spironolactone 50 mg/day without rescue therapy during the double-blind period. Started Oct 2023; status: active, not recruiting.

02

Drugs

sodium zirconium cyclosilicate
03

Conditions

hyperkalemiaheart failure with reduced ejection fraction (HFrEF)

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