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Phase I/II SOX + nivolumab with BBT-based S-1 dose adjustment in HER2-negative advanced gastric cancer

jRCTs031230127Phase 2Active, not recruiting

Start
Aug 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of tegafur, oxaliplatin and nivolumab in gastric cancer (GC) and gastroesophageal junction adenocarcinoma. Primary endpoints: Dose-limiting toxicities, Response rate and 1 more. Started Aug 2023; status: active, not recruiting.

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Drugs

tegafuroxaliplatinnivolumab
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Conditions

gastric cancer (GC)gastroesophageal junction adenocarcinoma

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