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STRASS 2 / JCOG2214INT neoadjuvant chemotherapy versus surgery alone for high-risk retroperitoneal sarcoma

jRCTs031230482Phase 3Recruiting

Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Start
Sep 2024
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial of doxorubicin, ifosfamide and dacarbazine in retroperitoneal leiomyosarcoma (RLMS) and dedifferentiated liposarcoma (DDL) (2 arms), sponsored by Cancer Institute and Hospital, Chinese Academy of Medical Sciences. Primary endpoint: Disease-free survival. Started Sep 2024; status: recruiting.

02

Drugs

doxorubicinifosfamidedacarbazine
03

Conditions

retroperitoneal leiomyosarcoma (RLMS)dedifferentiated liposarcoma (DDL)

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