Trial intelligence / Profile preview

GENTLE-Z trial of initial zolbetuximab dose adjustment plus chemotherapy in CLDN18.2-positive HER2-negative advanced gastric or related adenocarcinomas

jRCTs031240347Phase 2Recruiting

Start
Sep 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of zolbetuximab in gastric cancer (GC), gastroesophageal junction adenocarcinoma and esophageal adenocarcinoma (EAC) (2 arms). Primary endpoint: Vomiting-free rate in the first cycle. Started Sep 2024; status: recruiting.

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Drugs

zolbetuximab
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Conditions

gastric cancer (GC)gastroesophageal junction adenocarcinomaesophageal adenocarcinoma (EAC)

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