Trial intelligence / Profile preview

CASTLE phase II carboplatin plus nab-paclitaxel rechallenge in NSCLC with interstitial lung disease

jRCTs031240743Phase 2Recruiting

Sponsor
Chiba University Hospital
Start
Jun 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of carboplatin and paclitaxel in non-small cell lung cancer (NSCLC) and interstitial lung disease (ILD), sponsored by Chiba University Hospital. Primary endpoint: 3-month progression-free survival without acute exacerbation of interstitial lung disease rate. Started Jun 2025; status: recruiting.

02

Drugs

carboplatinpaclitaxel
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Conditions

non-small cell lung cancer (NSCLC)interstitial lung disease (ILD)

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