Trial intelligence / Profile preview

Phase II study of gumarontinib for MET exon 14 skipping mutation-positive advanced non-small cell lung cancer with intracranial metastases

jRCTs031260171Phase 2Recruiting

Sponsor
Taiho Pharmaceutical Co., Ltd.
Start
Jun 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
2
01

Overview

Phase 2, open-label, single-arm trial of glumetinib in non-small cell lung cancer (NSCLC), sponsored by Taiho Pharmaceutical Co., Ltd. Primary endpoint: Objective response rate of intracranial metastases. Started Jun 2026; status: recruiting.

02

Drugs

glumetinib
03

Conditions

non-small cell lung cancer (NSCLC)

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