Trial intelligence / Profile preview

PEARL5 study of DA-EPOCH-R plus high-dose methotrexate in newly diagnosed CD5-positive DLBCL

jRCTs041180159Phase 2Completed

Sponsor
Japan Agency for Medical Research and Development
Start
Nov 2012
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of rituximab, etoposide, prednisone, vincristine, cyclophosphamide and 2 more in diffuse large B-cell lymphoma (DLBCL), sponsored by Japan Agency for Medical Research and Development. Primary endpoint: 2-year progression-free survival rate. Started Nov 2012; status: completed.

02

Drugs

rituximabetoposideprednisonevincristinecyclophosphamide
03

Conditions

diffuse large B-cell lymphoma (DLBCL)

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