Trial intelligence / Profile preview

Dasatinib plus chemotherapy for newly diagnosed pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia

jRCTs041190067Phase 2Active, not recruiting

Sponsor
Japan Agency for Medical Research and Development
Start
Oct 2019
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of dasatinib in acute lymphoblastic leukemia (ALL) (2 arms), sponsored by Japan Agency for Medical Research and Development. Primary endpoints: 3-year event-free survival and Transplantation avoidance rate in first complete remission. Started Oct 2019; status: active, not recruiting.

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Drugs

dasatinib
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Conditions

acute lymphoblastic leukemia (ALL)

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