Trial intelligence / Profile preview

JPLSG-LCH-19-MSMFB phase II risk-specific trial in pediatric and young adult Langerhans cell histiocytosis

jRCTs041210027Phase 2Recruiting

Sponsor
Japan Agency for Medical Research and Development
Start
Jul 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
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Overview

Phase 2, open-label trial of dexamethasone, cytarabine and zoledronic acid in Langerhans cell histiocytosis (LCH) (2 arms), sponsored by Japan Agency for Medical Research and Development. Primary endpoints: 3-year event-free survival rate by risk group in patients under 20 years and 3-year event-free survival rate in patients 20 years and older. Started Jul 2021; status: recruiting.

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Drugs

dexamethasonecytarabinezoledronic acid
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Conditions

Langerhans cell histiocytosis (LCH)

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