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DURABLE trial of durvalumab monotherapy in unresectable hepatocellular carcinoma with Child-Pugh B

jRCTs041250091Phase 2Recruiting

Sponsor
Japan Oncology Network in Hepatobiliary and Pancreas
Start
Feb 2026
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of durvalumab in hepatocellular carcinoma (HCC), sponsored by Japan Oncology Network in Hepatobiliary and Pancreas. Primary endpoint: Frequency of treatment-related severe adverse events within 6 months. Started Feb 2026; status: recruiting.

02

Drugs

durvalumab
03

Conditions

hepatocellular carcinoma (HCC)

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