Trial intelligence / Profile preview

End Zoster-J study of Shingrix immune response in Japanese rheumatoid arthritis patients on methotrexate and/or upadacitinib

jRCTs051220105Active, not recruiting

Sponsor
AbbVie Inc.
Start
Dec 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Open-label trial of Zoster vaccine recombinant, upadacitinib and methotrexate in herpes zoster (HZ) (3 arms), sponsored by AbbVie Inc. Primary endpoint: Immunogenicity 4 weeks after second Shingrix dose. Started Dec 2022; status: active, not recruiting.

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Drugs

Zoster vaccine recombinantupadacitinibmethotrexate
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Conditions

herpes zoster (HZ)

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