Trial intelligence / Profile preview

OXA-REPLACE trial of mFOLFOX6 plus nivolumab in previously untreated unresectable or recurrent esophageal cancer

jRCTs051240108Phase 2Active, not recruiting

Start
Sep 2024
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of nivolumab, fluorouracil, oxaliplatin and levoleucovorin in esophageal cancer. Primary endpoint: Overall response rate. Started Sep 2024; status: active, not recruiting.

02

Drugs

nivolumabfluorouraciloxaliplatinlevoleucovorin
03

Conditions

esophageal cancer

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