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Vitamin D sufficiency and bone/muscle effects during weekly GH replacement in adult GH deficiency

jRCTs051250164Recruiting

Sponsor
Novo Nordisk
Start
Apr 2026
Modality
Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Randomised, open-label trial in adult onset growth hormone deficiency (AGHD) and Vitamin D deficiency (VDD) comparing Somatropin + alfacalcidol, Somatropin alone and Alfacalcidol alone (3 arms). Primary endpoint: Change in lumbar spine bone mineral density. Started Apr 2026; status: recruiting.

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Drugs

somatropinalfacalcidol
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Conditions

adult onset growth hormone deficiency (AGHD)Vitamin D deficiency (VDD)

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