Trial intelligence / Profile preview

PK and optimal dosing of cefmetazole, flomoxef and ceftolozane-tazobactam for SSI prophylaxis after lower GI surgery

jRCTs061190025Completed

Start
Jan 2020
Modality
Small Molecules
Countries
1
01

Overview

Open-label trial of cefmetazole, flomoxef and ceftolozane + tazobactam in surgical site infection (SSI) and Extended-spectrum beta-lactamase-producing Escherichia coli infection (3 arms). Primary endpoint: Pharmacokinetic parameters of cefmetazole, flomoxef and ceftolozane-tazobactam. Started Jan 2020; status: completed.

02

Drugs

cefmetazoleflomoxefceftolozane + tazobactam
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Conditions

surgical site infection (SSI)Extended-spectrum beta-lactamase-producing Escherichia coli infection

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