Trial intelligence / Profile preview

SPIRAL II: Osimertinib plus bevacizumab in untreated EGFR-mutated NSCLC with malignant pleural/pericardial effusion

jRCTs071180004Phase 2Completed

Sponsor
AstraZeneca
Start
Jan 2019
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of osimertinib and bevacizumab in non-small cell lung cancer (NSCLC), malignant pleural effusion (MPE) and malignant pericardial effusion (MPE), sponsored by AstraZeneca. Primary endpoint: 1-year progression-free survival rate. Started Jan 2019; status: completed.

02

Drugs

osimertinibbevacizumab
03

Conditions

non-small cell lung cancer (NSCLC)malignant pleural effusion (MPE)malignant pericardial effusion (MPE)

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