Trial intelligence / Profile preview

NIke Study: nivolumab + ipilimumab with platinum-doublet chemotherapy for untreated brain metastases in advanced non-small cell lung cancer

jRCTs071210019Phase 2Completed

Sponsor
Ono Pharmaceutical
Start
May 2021
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of nivolumab, ipilimumab, carboplatin, pemetrexed and paclitaxel in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Ono Pharmaceutical. Primary endpoint: Response rate of brain metastases. Started May 2021; status: completed.

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Drugs

nivolumabipilimumabcarboplatinpemetrexedpaclitaxel
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Conditions

non-small cell lung cancer (NSCLC)

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