Trial intelligence / Profile preview

Dabrafenib plus trametinib in pediatric BRAF V600 mutant progressive glioma

jRCTs071210071Completed

Start
Dec 2021
Modality
Small Molecules
Countries
1
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Overview

Open-label, single-arm trial of dabrafenib + trametinib and trametinib in glioma, low-grade glioma (LGG) and high-grade glioma (HGG). Primary endpoint: Best overall response up to 16 weeks after treatment initiation. Started Dec 2021; status: completed.

02

Drugs

dabrafenib + trametinibtrametinib
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Conditions

gliomalow-grade glioma (LGG)high-grade glioma (HGG)

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