Trial intelligence / Profile preview

V-ALERT Study of VTE incidence during amivantamab + lazertinib with apixaban prophylaxis in EGFR-mutant NSCLC

jRCTs071250140Phase 2Recruiting

Sponsor
Janssen Pharmaceutical
Start
Apr 2026
Modality
Small Molecules, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of amivantamab, lazertinib and apixaban in non-small cell lung cancer (NSCLC) and venous thromboembolism (VTE), sponsored by Janssen Pharmaceutical. Started Apr 2026; status: recruiting.

02

Drugs

amivantamablazertinibapixaban
03

Conditions

non-small cell lung cancer (NSCLC)venous thromboembolism (VTE)

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