Trial intelligence / Profile preview

Phase II G-ICE with MRD/PET-guided ASCT strategy in relapsed/refractory diffuse large B-cell lymphoma

KCT0011836Phase 2Recruiting

Sponsor
Roche
Start
Aug 2026
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of glofitamab, ifosfamide, carboplatin, etoposide and obinutuzumab in diffuse large B-cell lymphoma (DLBCL) (3 arms), sponsored by Roche. Primary endpoint: Complete response rate after completion of treatment. Started Aug 2026; status: recruiting.

02

Drugs

glofitamabifosfamidecarboplatinetoposideobinutuzumab
03

Conditions

diffuse large B-cell lymphoma (DLBCL)

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