Trial intelligence / Profile preview

Inclisiran in adults with homozygous familial hypercholesterolemia

MOH_2019-02-14_005959Phase 3Completed

Sponsor
Novartis
Start
Jan 2019
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial in familial hypercholesterolemia (FH) comparing Inclisiran then open-label inclisiran with Placebo then switch to open-label inclisiran (2 arms). Started Jan 2019; status: completed.

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Drugs

inclisiran
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Conditions

familial hypercholesterolemia (FH)

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