Trial intelligence / Profile preview

LEAP-006 first-line lenvatinib plus pembrolizumab and platinum-pemetrexed in metastatic nonsquamous NSCLC

MOH_2019-02-26_004927Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Jan 2019
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial of lenvatinib, pembrolizumab, pemetrexed, carboplatin and cisplatin in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Merck & Co. Primary endpoints: Safety of lenvatinib in combination, Disease control / progression delay and 1 more. Started Jan 2019; status: active, not recruiting.

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Drugs

lenvatinibpembrolizumabpemetrexedcarboplatincisplatin
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Conditions

non-small cell lung cancer (NSCLC)

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