Trial intelligence / Profile preview

Phase 2 open-label TIL + high-dose IL-2 after lymphodepleting chemotherapy for metastatic bladder cancer

MOH_2020-05-03_008898Phase 2Not yet recruiting

Sponsor
פרופ' גל מרקל
Start
Sep 2019
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of GC101 TIL + pembrolizumab, aldesleukin, cyclophosphamide and fludarabine in bladder cancer and transitional cell carcinoma (TCC), sponsored by פרופ' גל מרקל. Primary endpoints: Clinical benefit rate and Safety and tolerability. Planned start Sep 2019; status: not yet recruiting.

02

Drugs

GC101 TIL + pembrolizumabaldesleukincyclophosphamidefludarabine
03

Conditions

bladder cancertransitional cell carcinoma (TCC)

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