Trial intelligence / Profile preview

HER2CLIMB-02: tucatinib or placebo plus T-DM1 in HER2-positive metastatic or unresectable locally advanced breast cancer

MOH_2020-10-05_009382Phase 3Not yet recruiting

Sponsor
Seagen
Start
Jun 2020
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial of tucatinib and trastuzumab emtansine in breast cancer (2 arms), sponsored by Seagen. Primary endpoint: Progression-free survival. Planned start Jun 2020; status: not yet recruiting.

02

Drugs

tucatinibtrastuzumab emtansine
03

Conditions

breast cancer

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