Trial intelligence / Profile preview

Phase 1b/2 study of immunotherapy plus targeted therapy combinations in first-line advanced clear cell renal cell carcinoma (MK-3475-U03 substudy 03A)

MOH_2020-11-02_009048Phase 2Active, not recruiting

Sponsor
Merck & Co.
Start
Aug 2020
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of pembrolizumab, lenvatinib, belzutifan, mk-4830, quavonlimab + pembrolizumab and 1 more in clear cell renal cell carcinoma (ccRCC) (5 arms), sponsored by Merck & Co. Primary endpoints: Efficacy and Safety. Started Aug 2020; status: active, not recruiting.

02

Drugs

pembrolizumablenvatinibbelzutifanmk-4830quavonlimab + pembrolizumab
03

Conditions

clear cell renal cell carcinoma (ccRCC)

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