Trial intelligence / Profile preview

Phase 1b/2 immunotherapy and targeted therapy combinations in previously treated advanced clear cell renal cell carcinoma (U03 Substudy 03B)

MOH_2020-11-02_009049Phase 2Completed

Sponsor
Merck & Co.
Start
Aug 2020
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of pembrolizumab, lenvatinib, belzutifan, mk-4830, quavonlimab and 1 more in renal cell carcinoma (RCC) (6 arms), sponsored by Merck & Co. Primary endpoints: Safety and tolerability and Efficacy. Started Aug 2020; status: completed.

02

Drugs

pembrolizumablenvatinibbelzutifanmk-4830quavonlimab
03

Conditions

renal cell carcinoma (RCC)

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