Trial intelligence / Profile preview

Pembrolizumab versus platinum-doublet chemotherapy as first-line treatment for dMMR advanced or recurrent endometrial cancer

MOH_2022-03-08_010567Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Feb 2022
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of pembrolizumab, carboplatin and paclitaxel in endometrial cancer (EC) and endometrial carcinosarcoma (2 arms), sponsored by Merck & Co. Primary endpoint: Progression-free survival. Started Feb 2022; status: active, not recruiting.

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Drugs

pembrolizumabcarboplatinpaclitaxel
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Conditions

endometrial cancer (EC)endometrial carcinosarcoma

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